REPOSITORI BADAN LITBANG KESEHATAN RI

Penetapan Standar Nasional dari Vaksin DPT

Prijanto, Muljati (1982) Penetapan Standar Nasional dari Vaksin DPT.

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Abstract

To check the potency of DPT vaccine, standard preparations of the components, namely Adsorbed Diphtheria Toxoid, Pertussis Vanccine, and Adsorbed Tetanus Toxoid are necessary. Since WHO International Standard Preparations are distributed only in limited amounts, WHO has suggested that each member country shold develop a National Standard, which is to be matched with International Standard Preparations An Indonesian National standard of DPT vaccine (lot 1) has been prepared and lyophilized at the National Institute of Health in Tokyo. The potency of the National Standard of Pertussis Vaccine was determined by Active Mouse Protection Test (AMPT). After several experiments, the potency of the National Standard of Pertussis Vaccine has been decided of being 12 IU/ml. Using the same standard preparations, namely the National standard, It is hoped that from a lot of DPT vaccine, similiar result of potency could be achieved when determined by Goverment Vaccine Quality Control laboratory and the Manufacturer's laboratory.

Item Type: Article
Uncontrolled Keywords: DIPHTHERIA-TETANUS-PERTUSSIS VACCINE; DPT vaccine; buletin penelitian kesehatan; P5-BPPK
Subjects: W Medicine and related subjects (NLM Classification) > WC Communicable Diseases > WC 195-425 Infection. Bacterial Infections
Divisions: Pusat Penelitian dan Pengembangan Pemberantasan Penyakit
Depositing User: Administrator Eprints
Date Deposited: 02 Oct 2017 05:26
Last Modified: 14 Nov 2017 07:57
URI: http://repository.bkpk.kemkes.go.id/id/eprint/198

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